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On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians who will be struggling with alcoholism will manage to benefit especially from naltrexone, among three medications authorized by the U.S. Food and Drug Administration (FDA) for that treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a very particular mutation that makes them prone to benefit from naltrexone, compared with about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are presently available online ( within the journal Neuropsychopharmacology and you will be published in an upcoming print edition in the journal.

Using two separate drugs to lose weight naturally can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the people that go through it one should err on the side of caution and permit the FDA do its job and demand some study be done so that the public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to make money and that they would say everything to keep people on their own medications.

Researchers discovered that participants taking this drug for the year, lost weight within 4 weeks and have kept the load off throughout the 56 weeks from the study. Contrave is a combination with the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which can be made up of multiple active ingredient, which can make them far better and safer.

Combo-pilling will be the newest fad or in addition to this the newest ahead under scrutiny and therefore it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular is the fact that as of right now there are no long term prescription slimming capsules that have been licensed by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures really are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug could also raise blood pressure level and heart rate, and shouldn't be used in people with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure and heartbeat and must not be used in patients with uncontrolled high blood pressure levels, as well as by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients having a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients towards the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.


Most of the combinations that are used to enhance fat loss involve an amphetamine with an antidepressant. Phentermine and Prozac really are a popular combination that have been around for a long time, and although it has been around nobody wants to truly combine the 2 and try to get FDA approval to market it as a weight-loss pill. Right there should raise some warning flags if the greedy pharmaceutical companies do not want to be involved in combining medications and selling them something has to be wrong with all the combination. In fairness there is certainly one fat loss combination pill that's in front of the FDA now Contrave?which couples naltrexone, accustomed to treat alcohol and substance abuse, using the antidepressant bupropion (Wellbutrin, Zyban) it has been given the just do it to move forward by an FDA advisory committee, but as of yet hasn't been approved.